Clinicopathological factors

Variables

Postoperative adjuvant chemotherapy

P-value

Present (n = 162)

Absent (n = 72)

Age

≥75

15

27

<0.001

<75

147

45

Gender

Male

96

36

0.20

Female

66

36

Location

Proximal

51

19

0.54

Distal

111

53

Preoperative CEA

Elevated

71

30

0.78

Normal

91

42

Differentiation

Low gradea

151

67

>0.99

High gradeb

11

5

Invasion depth

T1 - T3

94

55

0.008

T4

68

17

Lymphatic invasion

None-mild

46

32

0.02

Moderate-severe

116

40

Venous invasion

None-mild

79

52

0.001

Moderate-severe

83

20

No. of dissected lymph nodes

≥12

129

53

0.31

<12

33

19

TNM classification, 7th edition

IIIA, IIIB

129

63

0.20

IIIC

33

9